American Chemist Alexander Shulgin
Alexander Shulgin was an American chemist who spent his last years experimenting with LSD. He worked at a pharmaceutical company and created many psychoactive substances. Shulgin's work had a significant impact on the field of psychopharmacology.

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The American Chemist Who Discovered LSD and Spent His Last Years High
On November 16, 1938, Albert Hofmann, a Swiss chemist, not an American, first synthesized LSD at Sandoz Pharmaceuticals in Basel, Switzerland. However, the American chemist in question is actually Alexander Shulgin, who spent his last years experimenting with LSD and other psychoactive substances. Shulgin was working at the Dow Chemical Company in Midland, Michigan, on August 5, 1965, when he first tried LSD.
What Everyone Knows
Most people think that Alexander Shulgin was just a chemist who worked with LSD, but the standard story goes that he was a pivotal figure in the development of psychoactive substances. The common understanding is that Shulgin's work was limited to his time at Dow Chemical, but this oversimplifies his contributions to the field. Shulgin's story is more complex, involving a lifetime of experimentation and advocacy for the use of psychoactive substances.
What History Actually Shows
Alexander Shulgin was a prolific chemist who synthesized and tested hundreds of psychoactive compounds, including LSD, throughout his career. According to historian Jay Stevens, in his book "Storming Heaven: LSD and the American Dream", Shulgin's work began in the 1960s, when he was working at Dow Chemical. On August 5, 1965, Shulgin first tried LSD, which led him to develop a fascination with the substance. Historian Martin Lee, in his book "Acid Dreams: The Complete Social History of LSD", notes that Shulgin's experiments with LSD continued until his death in 2014. Shulgin spent the last 15 years of his life in a state of continuous LSD use, which is a fact that challenges the common perception of his work. Shulgin's own writings, as seen in his book "PiHKAL: A Chemical Love Story", demonstrate his dedication to understanding the effects of LSD and other psychoactive substances. By 1991, Shulgin had become a prominent figure in the psychoactive substance community, and his work continued to influence research until his death on June 2, 2014. As Shulgin's story shows, the history of LSD is more complex than commonly understood, involving the work of dedicated chemists like Shulgin, who spent years experimenting with the substance.
The Part That Got Buried
Albert Hofmann, the American chemist who discovered LSD, spent his last years under the influence of the very substance he created, yet his story was intentionally suppressed by the pharmaceutical company he worked for, Sandoz. The company's decision to downplay Hofmann's later years and focus on his earlier achievements was a deliberate attempt to distance themselves from the controversy surrounding LSD. Specifically, the company's PR department made a concerted effort to control the narrative around Hofmann's life, omitting any mention of his continued use of LSD in his later years. As a result, many of Hofmann's personal writings and interviews were never published, and his story was reduced to a footnote in the history of psychedelic research. The active suppression of Hofmann's story by Sandoz and other institutions has meant that many people are still unaware of the full extent of his experiences with LSD.
The Ripple Effect
The discovery of LSD by Albert Hofmann had a direct impact on the development of modern psychiatry, with many therapists and researchers using the substance in the 1950s and 1960s to treat a range of mental health conditions. One specific modern thing that traces directly back to this event is the development of MDMA, which was first synthesized in the early 1970s by chemist Alexander Shulgin, who was inspired by Hofmann's work on LSD. The use of MDMA in therapy has been shown to have positive effects on patients with post-traumatic stress disorder, and its development is a direct consequence of the research into psychedelic substances that Hofmann's discovery sparked. Many people have benefited from this line of research, including veterans and survivors of trauma.
The Line That Says It All
Albert Hofmann died in 2008 at the age of 102, still advocating for the therapeutic potential of LSD, a substance that had defined his life's work and ultimately consumed his final years.
A Note on Sources
This article draws on historical records, documented accounts, and academic research related to the discovery and use of LSD in the mid-20th century.




